From Trials to “Real Life”

[Risedronate (Actonel)--from randomized clinical trials to real life].

Idiopathic pulmonary fibrosis: from clinical trials to real-life experiences.

Randomised controlled clinical trials are fundamental in medicine to develop new effective drugs and new therapeutic regimens and are the strength of evidence-based medicine. These studies allow us to avoid the repetition of misleading experiences that have been reported in the past, where drugs or associations were utilised without compelling evidence and ultimately proven to be ineffective. I...

Slowing progression of idiopathic pulmonary fibrosis with pirfenidone: from clinical trials to real-life experience

Idiopathic pulmonary fibrosis (IPF) is a rare, progressive, irreversible and eventually fatal fibrosing lung disease. Pirfenidone is the only approved therapy for reducing disease progression indicated in adult patients with mild to moderate IPF, which is considered the best attainable goal for a progressive and irreversible disease like IPF. Pirfenidone is an orally active, small molecule with...

Acute gastroenteritis: from guidelines to real life

Acute gastroenteritis is a very common disease. It causes significant mortality in developing countries and significant economic burden to developed countries. Viruses are responsible for approximately 70% of episodes of acute gastroenteritis in children and rotavirus is one of the best studied of these viruses. Oral rehydration therapy is as effective as intravenous therapy in treating mild to...

Romero's Odyssey to Santa Fe: from Simulation to Real Life

Many a researcher in evolutionary robotics would love to have at his or her disposal a real population of bopping critters. Toward this end, the ultimate goal of our work is twofold: (1) to build a robot that is cheap, modular, and adaptable; and (2) to use a population of such robots in evolutionary-robotics experiments. As a rst step in the study of adaptive robotics using populations of chea...